Order beneath the trip, another look at MDMA & a microdosing finding worth watching. 1. Your Brain on Mushrooms Isn’t Just Descending Into Chaos Synopsis: Researchers scanned 62 psychedelic-naive adults before and under psilocybin during rest, meditation, music & a video. Their analysis revealed organized patterns of brain
Welcome to The Psychedelic Blog. A bestselling publication exploring altered states & the culture surrounding them. This week: Why the future of Psychedelics is in the living room, not the clinic. Spend enough time reading about Psychedelics & you come away thinking every trip needs a treatment plan or a
1. Psilocybin & LSD Advance Toward FDA Approval Synopsis: New Psychology Today overview examines the progress of Psilocybin & LSD through late-stage trials. It highlights reported positive Phase 3 results for treatment-resistant depression & generalized anxiety disorder, while emphasizing that company announcements aren’t FDA approval. My take:
Welcome to The Psychedelic Blog. An independent media platform covering drugs, altered states & the culture surrounding them. This week: The 3rd edition of a monthly series featuring 7 questions about Psychedelics I can’t stop thinking about. 1. When does “everything you need is within” become an excuse not
🍃 Ayahuasca-Assisted Therapy Shows Promise for Severe Grief Synopsis: Researchers studied 84 adults experiencing severe grief within a year of losing a close family member. Participants received meaning reconstruction therapy combined with 2 Ayahuasca sessions, therapy alone or no treatment. Grief decreased in all 3 groups, but the Ayahuasca group
Welcome to The Psychedelic Blog. An independent media platform covering drugs, altered states & the culture surrounding them. This week: Ancient teeth, psychoactive betel nuts & the 25,000-year fantasy of a drug-free society. Archaeologists studying the teeth of ancient hunter-gatherers in Indonesia found evidence that they
Synopsis: In a new study, researchers gave male rats Psilocybin 1 year after they sustained traumatic brain injuries. A single dose improved movement, learning & memory while restoring disrupted serotonin signaling & reducing the number of microglial cells associated with the brain’s response to injury. My take: I love
Independent reporting & ideas on drugs, altered states & the culture surrounding them.
Synopsis: In a small study, 14 people with bipolar II depression received Psilocybin alongside psychotherapy. Depression scores improved, but 3 participants experienced notable psychiatric events, including suicidal thoughts or hypomania. The trial had no placebo group, so it cannot establish that Psilocybin caused the improvement. My take: People with bipolar
The “microdose” I intended on taking was definitely closer to a journey. After exploring its intense aphrodisiac qualities with a friend…I wrote a multi-page manifesto on the balcony about the direction I want to take in the next chapter of my life. Life is electric.
Welcome to The Psychedelic Blog. An independent media platform covering drugs, altered states & the culture surrounding them. This week: The FDA sketches a faster path, LSD clears another major trial, Psilocybin shows promise beyond mental health & researchers ask how you give someone a believable fake trip. Plus, the
Monday, September 14, 2026 🏛️ The FDA Wants Psychedelic Treatments to Reach Patients Faster Synopsis: The FDA is supporting faster development & review of Psychedelic medicines through priority vouchers, finalized clinical-trial guidance & new research. Its efforts include Psilocybin for depression, Methylone for PTSD & an early-stage study of
42-year-old man, Italy Found dead after using Kambo. The frog secretion peptide deltorphin A was detected in his blood. Natasha Lechner, 39, Australia, 2019 Died shortly after a Kambo ceremony. Medical experts concluded an acute coronary event was the likely cause. Jarrad Antonovich, 46, Australia, 2021 Died after
Welcome to The Psychedelic Blog. An independent media platform covering drugs, altered states & the culture surrounding them. This week: Why our definition of “sober” no longer makes sense…and what we should be asking instead. We’re all addicts. We just arbitrarily label some addictions destructive while ignoring, accepting
Synopsis: Archaeologists studying the teeth of ancient hunter-gatherers in Indonesia found evidence that people were sucking psychoactive Betel Nuts as far back as 25,000 years ago. The discovery predates agriculture & is now considered the earliest direct evidence of habitual human drug use. My Take: I’ve said
💰 Musk’s Inner Circle Is Betting Big on Psychedelics Synopsis: 2 longtime Elon Musk allies & SpaceX directors, Antonio Gracias & Steve Jurvetson, are putting millions behind efforts to move Psychedelics into mainstream medicine. Gracias’s family foundation reportedly invested $25 million to rescue the company formerly known as Lykos
Welcome to The Psychedelic Blog. An independent media platform covering drugs, altered states & the culture surrounding them. This week: The 2nd edition of a monthly series featuring 7 questions about Psychedelics I can’t stop thinking about. 1. What if the Psychedelic Renaissance is happening in the wrong places?
I sat down with Norman Ohler, bestselling author of Blitzed: Drugs in Nazi Germany and Tripped: Nazi Germany, the CIA, and the Dawn of the Psychedelic Age, to explore a question that runs quietly through his work: the role of psychoactive substances throughout human history. Our discussion moved across time